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Analysis of cross-reactive, pre-existing memory CD4+ T lymphocytes against SARS-CoV-2 and their role in SARS-CoV-2 immunity

  • Funded by The Structural Genomics Consortium (SGC)
  • Total publications:3 publications

Grant number: C-0072

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    The Structural Genomics Consortium (SGC)

  • Principal Investigator

    Zhihai Qin, Jun Dong

  • Research Location

    China, Germany

  • Lead Research Institution

    First Affiliated Hospital of Zhengzhou University, German Rheumatism Research Centre

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

3 Publications linked via Europe PMC

Last Updated:4 days ago

View all publications at Europe PMC

Methylomes of human CD4 and CD8 memory T lymphocytes reveal tissue-specific epigenetic signatures for maintenance and recall function.

Surface CD69-Negative CD4 and CD8 Bone Marrow-Resident Human Memory T Cells.

A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individuals.