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Swab-To-Pcr: Simple And Rapid Diagnosis Of Covid-19 Using Extraction-Free Nucleic Acid Amplification

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    Peter Wall Institute

  • Principal Investigator

    Peter Tilley

  • Research Location

    Canada

  • Lead Research Institution

    Department of Pathology and Laboratory Medicine, UBC

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Current COVID-19 tests are slow, expensive, and require complex kits which are frequently back-ordered in the United States. A major component of all the current COVID-19 tests in clinical labs is the RNA extraction step which takes hours and doubles the cost. In this study, we plan to use new polymerase enzymes to develop, validate, and implement simple and fast "extraction-free" tests which will provide high volume COVID-19 results in a timely manner. Following validation at BC Children's Hospital this summer and fall, the data and standard operating procedure will be offered to other labs throughout BC, via BCCDC.