Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Project Summary People with serious mental illness (SMI) and intellectual or developmental disabilities (IDD) are at a disproportionately high risk for COVID-19 and poor COVID-19 outcomes due to high rates of health-related risk factors and living in congregate care settings. Rates of COVID-19 for residents with SMI and IDD in this project are 8 times higher-12 percent-and for staff, 2 times higher-3 percent-compared to the general population in the surrounding "hot spot" communities (1.5 percent) selected for this study. We lack knowledge on how to best adapt, prioritize, deliver, and implement effective COVID-19 prevention strategies for this highly vulnerable population and the staff who provide their care. Study Questions With the goal of prioritizing and resourcing actionable best practices, what is the comparative effectiveness of different types and intensities of four basic preventive interventions-screening, isolation, contact tracing, personal protective practices-in reducing rates of COVID-19 and related hospitalization and mortality in staff and adult residents with SMI and IDD in congregate care settings? With the goal of effectively implementing best practices, what is the most effective implementation strategy to reduce rates of COVID-19 in congregate care settings for persons with SMI and IDD: (1) Tailored Best Practices (TBP) specifically adapted for staff and residents with SMI and IDD in congregate living settings, or (2) Generic Best Practices (GBP) consisting of standard guidelines for all congregate care settings? Study Description We will employ a Hybrid Type-II Effectiveness-Implementation study design and will address the following study aims: Aim 1: Synthesize Baseline Data: (a) Synthesize existing data on (1) rates of COVID-19 and related hospitalization and mortality; (2) use of screening, isolation, contact tracing, and personal protective practices in 400 group homes for SMI and IDD; and (3) barriers and facilitators to implementing recommended practices. Aim 2: Evaluate Effectiveness: Determine the comparative effectiveness of different COVID-19 preventive practices-screening, isolation, contact tracing, use of PPE-for residents and staff of group homes for SMI and IDD using a validated COVID-19 simulation model with data from Aim 1. Aim 3: Evaluate Implementation: Determine comparative effectiveness of implementing Tailored Best Practices (TBP) determined in Aim 2 compared to Generic Best Practices (GBP) for 400 congregate care homes for SMI and for IDD using a cluster-randomized design.