Return to homepagePandemic Pact

Developing Methods and Guidance to Improve Hybrid Study Designs

  • Funded by Patient-Centered Outcomes Research Institute
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Known Financial Commitments (USD)

    $124,272

  • Funder

    Patient-Centered Outcomes Research Institute

  • Principal Investigator

    PhD. Jennifer Lund

  • Research Location

    United States of America

  • Lead Research Institution

    University of North Carolina at Chapel Hill

  • Research Priority Alignment

    N/A

  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This project's enhancement will use a modeling tool developed in the original study and expand its use to COVID-19-related clinical trials. The team will use aggregated data identified in published clinical trials on real-world patient populations. The review will be used as the foundation for applying the visualization tools to compare trial populations to various targets, including real-world critically ill patients and patients identified via publicly available surveillance data. The results from this study will help to improve the understanding of the representativeness and generalizability of randomized controlled trials that assess treatments for COVID-19 and identify shifts in types of patients impacted by the pandemic over time to inform future waves of infection.