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Developing Portable Magnetic Bio-assay Platforms for the Detection of SARS-COV-2

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    University of Minnesota

  • Principal Investigator

    PhD. Jian-Ping Wang, MVSc. Maxim Cheeran

  • Research Location

    United States of America

  • Lead Research Institution

    College of Science and Engineering, University of Minnesota

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

A simple, rapid, and sensitive diagnostic test for detection of SARS-CoV-2 that can be performed in a point-of-care setting would greatly benefit implementation of appropriate control and prevention strategies. Led by Jian-Ping Wang, PhD, professor of electrical and computer engineering, and Maxim Cheeran, MVSc, PhD, associate professor of veterinary population medicine, this study will use two portable magnetic biosensing kits based on giant magnetoresistance (GMR) and magnetic particle spectroscopy (MPS) for the detection of the Spike protein (S) and two different epitopes of nucleocapsid (N) protein of SARS-CoV-2. Expected output of this project is a new diagnostic test based on GMR and MPS platforms for simultaneous detection of key SARS-COV-2 antigens, fully validated using experimental, and field samples, and ready for on-site testing and subsequent implementation for routine diagnosis for households.