Mouse Model Host for SARS-CoV-2

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $0
  • Funder

    University of Minnesota
  • Principal Investigator

    PhD. Michael Koob
  • Research Location

    United States of America
  • Lead Research Institution

    Medical School, University of Minnesota
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Disease models

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Led by Michael Koob, PhD, associate professor, Department of Lab Medicine and Pathology, researchers in this study will make new mouse models that precisely mimic the same ACE2 gene expression found in humans, and will partner with JAX labs to rapidly establish breeding colonies to make these models available worldwide. "We have pioneered and optimized the methods needed to conduct these gene-replacement projects, and do not know of any other lab in the world that can currently match our ability to do this work," said Koob.