Understanding Critical Virus-Host Interactions During the Life Cycle of SARS Coronavirus-2

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $0
  • Funder

    University of Minnesota
  • Principal Investigator

    PhD. Anja Bielinsky
  • Research Location

    United States of America
  • Lead Research Institution

    College of Biological Sciences, University of Minnesota
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Led by Anja Bielinsky, PhD, professor of biochemistry, molecular biology, and biophysics, this study will determine how the host enzyme DDX1 physically interacts with the N-protein. "Blocking the interaction between N-protein and DDX1 will be useful for the development of therapeutic agents that disrupt the life cycle of CoV," said Bielinsky.