Return to homepagePandemic Pact

Modeling of Virus/Medicine Transport in Respiratory Systems and Their Interactions with Epithelial Cells for COVID-19 Treatment

Grant number: unknown

Grant search

Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    University of Minnesota

  • Principal Investigator

    PhD. Suo Yang

  • Research Location

    United States of America

  • Lead Research Institution

    Institute for Engineering in Medicine, University of Minnesota

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Led by Suo Yang, PhD, Richard & Barbara Nelson Assistant Professor, College of Science and Engineering, researchers in the study will conduct modeling of the transport of virus aerosols and nasal medicinal droplets in the lung airways, and model lung inflammation to show the impact of inflammation on the diffusive transport of oxygen to the blood. "Based on the understanding of virus and medicine transport in respiratory systems, we can optimize the medicinal droplet size distribution and design medical spray injection systems accordingly," said Yang. "In addition, based on the understanding of the interactions between virus and medicine with epithelial cells, we can guide the medicine development and medication dosing and timing."