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LAMP-based molecular diagnostics or SARS-CoV-2

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.043E+13

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2021

  • Known Financial Commitments (USD)

    $418,571.65

  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)

  • Principal Investigator

    Dr ir. J Kieboom

  • Research Location

    Netherlands

  • Lead Research Institution

    TNO

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Research The method is based on the so-called loop-mediated isothermal amplification (LAMP) technology. LAMP testing is simpler than the standard PCR method currently in use and is also suitable for performing at sample collection locations. The LAMP test can be performed in parallel with the existing PCR tests and can thus increase the test capacity in the Netherlands. In this project TNO is collaborating with DSM, RIVM, LUMC, UMCG and Micronit on a LAMP test that is less dependent on suppliers of critical reagents. In addition, TNO, in collaboration with the GGD Amsterdam, will accelerate the clinical validation of the LAMP diagnostics and implement it on an existing test street. Expected outcomes This study is working towards a LAMP-based test method for COVID-19, whose materials and reagents will not be pressurized, a comprehensive clinical validation and an implementation plan for large-scale use of LAMP tests in the Netherlands.