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COMAIT-19: Understanding the functions of MAIT cells during COVID-19.

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    Thomas Baranek

  • Research Location

    France

  • Lead Research Institution

    Université de Tours

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The COMAIT-19 project, coordinated by Thomas Baranek (U 1100 - Center d'Etude des Pathologies Respiratoires (CEPR) - University of Tours), proposes to characterize immune signatures throughout the clinical management of severe forms of Covid -19, by focusing on MAIT (Mucosal Associated Invariant T) cells which are recruited from the upper airways and participate in the production of inflammatory cytokines. Using blood and respiratory fluid samples from patients, he will analyze the phenotype and functions of MAIT cells and study the transcriptomic signature of MAIT cells.