Consortium for Rapid COVID-19 Drug Development in Africa

  • Funded by African Academy of Sciences (AAS )
  • Total publications:2 publications

Grant number: SARSCov2-2-20-002

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Key facts

  • Disease

    COVID-19
  • Known Financial Commitments (USD)

    $200,000
  • Funder

    African Academy of Sciences (AAS )
  • Principal Investigator

    Prof. Ozlem Tastan Bishop
  • Research Location

    South Africa
  • Lead Research Institution

    Rhodes University
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Not applicable

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Candidate vaccines, diagnostics and therapeutics

Publicationslinked via Europe PMC

Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.

Evolutionary progression of collective mutations in Omicron sub-lineages towards efficient RBD-hACE2: Allosteric communications between and within viral and human proteins.