Targeted COVID-19 treatment using neutralizing antibody

  • Funded by The Research Council of Norway (RCN)
  • Total publications:6 publications

Grant number: 316294

Grant search

Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2021
  • Known Financial Commitments (USD)

    $464,000
  • Funder

    The Research Council of Norway (RCN)
  • Principal Investigator

    Olav Skjervold
  • Research Location

    Norway
  • Lead Research Institution

    Næringsliv
  • Research Priority Alignment

    N/A
  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Pending a vaccine and other effective treatments, Norimun AS, together with NTNU and Oslo University Hospital (OUS), has taken the initiative to produce targeted antibodies against SARS-CoV-2, the virus that causes COVID-19. To meet the demand for antibodies that can neutralize SARS-CoV-2, it must be produced in large quantities at a cost-effective price. Furthermore, antibody formulations that meet medical safety requirements must be prepared and a clinical trial on humans must be designed. An effective antibody preparation, which acts as a passive immunization, will be of great benefit to critically ill patients but also to healthcare professionals who are exposed to a high risk of infection. The main objective of the project is to produce antibodies with a neutralizing effect that can be offered to COVID-19 patients and administered either orally, by inhalation or by transfusion.

Publicationslinked via Europe PMC

Last Updated:an hour ago

View all publications at Europe PMC

Parallel evolution despite low genetic diversity in three-spined sticklebacks.

Cast away in the Adriatic: Low degree of parallel genetic differentiation in three-spined sticklebacks.

Author Correction: On the causes of geographically heterogeneous parallel evolution in sticklebacks.

Estimating uncertainty in divergence times among three-spined stickleback clades using the multispecies coalescent.

Cryptic temporal changes in stock composition explain the decline of a flounder (Platichthys spp.) assemblage.