Return to homepagePandemic Pact

Mutation dynamics of SARS-CoV-2 in Austria

Grant number: unknown

Grant search

Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2020

  • Known Financial Commitments (USD)

    $54,500

  • Funder

    WWTF Austria

  • Principal Investigator

    Andreas Bergthaler

  • Research Location

    Austria

  • Lead Research Institution

    Center for Molecular Medicine (CeMM)

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen genomics, mutations and adaptations

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

We lack comprehensive knowledge about how SARS-CoV-2 mutates in humans. The virologist Andreas Bergthaler and his interdisciplinary team will use high-throughput sequencing and complex computer analysis to decode the entire virus genome of patients. The rapid exchange of data from the first SARS-CoV-2 genomes from Austria provides epidemiologists with important information to reconstruct transmission chains and support political decision-makers, and offer valuable insights into the evolutionary dynamics of the devastating virus pandemic. A better molecular understanding of how mutations arise in the SARS-CoV-2 genome will also support the development of vaccines and antiviral drugs.