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Implementation of rapid diagnostics based on RPA technology. Covid-19 Rapid-Identification (CoRap-ID) test

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    MINCTCI - Chile

  • Principal Investigator

    N/A

  • Research Location

    Chile

  • Lead Research Institution

    Merken Biotech

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The CoRap-ID test is based on a combination of two technologies, isothermal RPA (recombinase polymerase amplification) and lateral flow tapes. The combination of these technologies allows the amplification of a characteristic gene sequence of the SARS-CoV2 virus and a rapid visualization of the amplification results without the need for additional equipment. CoRap-ID is based on the detection of viral RNA (N-gene) in a "one-step reaction"; that is, the Reverse Transcription (RT) reaction and the Polymerase Chain Reaction (PCR) are carried out in the same reaction tube, as in some real-time PCR kits currently used as "gold standard". " diagnosis.