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Demographics and other characteristics, comorbidities and risk factors for Covid-19 onset and prognosis

Grant number: 2020-02828

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Key facts

  • Disease

    COVID-19
  • Start & end year

    N/A
  • Known Financial Commitments (USD)

    $240,000
  • Funder

    FORMAS
  • Principal Investigator

    Professor Fredrik Nyberg
  • Research Location

    Sweden
  • Lead Research Institution

    University of Gothenburg
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

More scientific data on Covid-19 patients and their prognosis, as well as models and tools for predicting disease progression and supporting care and community planning, are needed both urgently and in the longer term. Risk groups, for example, appear to be cardiovascular and lung disease, but great ambiguities remain, and larger and better studies are needed. The acute nature of the pandemic means that this project was initiated with the greatest urgency. Objectives and Methods By linking data from national and regional health databases and quality registers, we will examine Covid-19 patients and a population comparison group to understand patients' characteristics (eg age, morbidity) and how, for example, comorbidity in cardiovascular disease, lung disease and diabetes, medication or other factors affect the risk of developing Covid-19, getting more serious illness, worsening, die or survive with sequelae. We update data frequently and can thus continuously research current results based on current data during the ongoing pandemic. Significance With broad objectives and current relevant register data, the project can support pandemic care with relevant research findings on Covid-19 patients, their risk factors and prognosis, and care needs in risk groups - and lead to better care and treatment. The broad research approach and focus on frequent updating of data are innovative aspects of the project. A broad cross-functional project group and dialogue with stakeholders are other important components. Significance With broad objectives and current relevant registry data, the project can support pandemic care with relevant research findings on Covid-19 patients, their risk factors and prognosis, and care needs in risk groups - and lead to better care and treatment. The broad research approach and focus on frequent updating of data are innovative aspects of the project. A broad cross-functional project group and dialogue with stakeholders are other important components. Significance With broad objectives and current relevant registry data, the project can support pandemic care with relevant research findings on Covid-19 patients, their risk factors and prognosis, and care needs in risk groups - and lead to better care and treatment. The broad research approach and focus on frequent updating of data are innovative aspects of the project. A broad cross-functional project group and dialogue with stakeholders are other important components.

23 Publications linked via Europe PMC

SARS-CoV-2 infection and COVID-19 vaccination and the risk for new-onset type 1 diabetes: a register-based population study in Sweden.

Risk of venous thromboembolism after SARS-CoV-2 vaccination-Evidence from genome-wide association study and population-based observational study.

Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre- and Post-COVID-19 in Sweden-An Interrupted Time Series Study.

Primary care pharyngotonsillitis complications following absent or deferred antibiotic treatment across the COVID 19 pandemic.

Covid-19 and cardiovascular disease in a total population-study of long-term effects, social factors and Covid-19-vaccination.

SARS-CoV-2 Infection Is Associated With an Increased Risk of Hospital-Treated Infectious Mononucleosis due to EBV: National Register-Based Cohort Study.

Area-related sociodemographic factors and the risk of severe COVID-19: a longitudinal study of the total adult population in Sweden.

Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID-19-A Nationwide Cohort Study.

Clarification on methodology used in the study investigating COVID-19 vaccination and cardiovascular events.