DETECTION AND RAPID CHARACTERIZATION OF COVID19 AND THE PATIENT

The life cycle of coronaviruses allows differentiation between the encapsulated virus and its infection and replication processes. We will develop modular kits that allow, on the one hand, to determine the presence of the virus, the presence of viral processes involved in the infection and the determination of those variables that may be relevant in the development of the disease (viral and human). The kits will be based on isothermal amplification and rapid PCR of the regions of interest and their rapid detection (15-30 minutes the presence of the virus, available in 1 - 2 months). In a second kit-module, from these amplified and those of interest in relation to the patient, libraries will be generated to be sequenced using Nanopore systems. This second part of the study will make it possible to know the strain of the virus and the variables of the patient that are relevant in the disease, making a report based on the available data and including other clinical variables of interest.