Analysis of soluble markers of immune activation and populations of CD8 NK and T cells in patients with SARS-CoV-2 infection

This study aims to generate knowledge about the populations of immune cells in charge of infection control, in order to understand the kinetics and magnitude of the immune response during the COVID-19 disease. This knowledge can identify biomarkers that contribute to: 1) identifying which patients will be more likely to experience respiratory failure requiring admission and respiratory support treatment in intensive care units, 2) monitoring the evolution of the infection, and 3) exploring new therapeutic interventions. All this not only seeks to contribute to personalizing the treatment based on the profile and immune response of each patient, but it will also result in a reduction of the stress of the health system by being able to predict in advance the patients who may develop more serious clinical pictures and therefore plan and optimize the use of the resources available by the health system