Genetic Determinants and Genomic Biomarkers of Risk in Patients With SARS-COV-2 Coronavirus Infection

Objective: Search for genomic risk biomarkers that may predispose to more serious infection prognostic stratification and / or response genomic biomarkers in patients who have received treatment during infarction. A whole genome association study (GWAS) will be carried out in a sample of 7000 Spanish patients and a whole genome sequencing study in a group of selected patients (300), collected by a national and international consortium that includes more than 15 hospitals. , complemented by a high-level research group. Clinical data (signs, symptoms and findings) and personal and epidemiological history will be collected in a common database designed ad hoc for this project. Thus, we will find genetic / genomic determinants of risk and poor evolution that allow a better stratification of patients and the adaptation and optimization of therapeutic protocols.