Immunological and virological factors in COVID-19 and their correlation with the evolution to severe forms of the disease.

Prospective study to be carried out at the Son Espases and Son LLátzer Hospitals in Palma de Mallorca, the objective of which is to identify virological and immunological factors, as well as clinical, radiological and analytical factors, related to severe forms of COVID-19. During the months of April and May 20120, 150 patients diagnosed with mild, severe and moderate COVID-19 will be recruited (50 patients in each group) and determinations will be made in peripheral blood of baseline levels and at 2 weeks of IL1, IL6, IL8, IL10, TNFa and IL2R, of lymphocyte subpopulations and complement study, as well as study of semiquantitative viral load in oropharynx and peripheral blood and production of Ab against SARS-COV-2. The relationship of these parameters with epidemiological, clinical and radiological variables of mild, severe and moderate COVID-2 will be analyzed.