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Determination of predictive phenotypes of complications in COVID-19 and evaluation of the efficacy of immunosuppressive treatments

  • Funded by National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)
  • Total publications:0 publications

Grant number: COV20_01031

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Funder

    National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)

  • Principal Investigator

    Jesús Rodríguez Baño

  • Research Location

    Spain

  • Lead Research Institution

    Fundación Publica Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI) Hospital Universitario Virgen Macarena

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Unspecified

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The objective of the project is (1) to identify predictive phenotypes of need for mechanical ventilation in the initial evaluation of patients and their evolution in the first days of admission, and (2) to evaluate the efficacy and safety of immunosuppressive treatments used in patients without Mechanical ventilation with elevation of macrophage activation syndrome markers. They will be carried out through multicenter retrospective cohort studies, with advanced statistical analysis for observational studies.