Changes in lung function tests in patients with CoVid19 pneumonia

  • Funded by National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)
  • Total publications:0 publications

Grant number: COV20_01209

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Key facts

  • Disease

    COVID-19
  • Funder

    National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)
  • Principal Investigator

    JAIME SIGNES-COSTA
  • Research Location

    Spain
  • Lead Research Institution

    FUNDACION HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The project consists of a prospective, observational, multicenter study that will evaluate the changes in lung function (forced spirometry, measurement of static lung volumes using plethysmography and carbon monoxide pulmonary diffusion test) that patients admitted with pneumonia will present. by CoVid19 according to the level of severity at 4 and 26 weeks after hospital discharge. Restrictive pulmonary alterations will be confirmed by imaging tests (high resolution chest CT). The presence of immune response phenomena that lead to pulmonary fibrosis will be related to demographic and clinical variables and a series of biological markers, some of them already described as co-participants in the pathogenesis of pulmonary interstitial diseases, specifically of the idiopathic pulmonary fibrosis.