Changes in lung function tests in patients with CoVid19 pneumonia
- Funded by National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)
- Total publications:0 publications
Grant number: COV20_01209
Grant search
Key facts
Disease
COVID-19Funder
National Institute of Health Carlos III [El Instituto de Salud Carlos III] (ISCIII)Principal Investigator
JAIME SIGNES-COSTAResearch Location
SpainLead Research Institution
FUNDACION HOSPITAL CLINICO UNIVERSITARIO DE VALENCIAResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Immunity
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
The project consists of a prospective, observational, multicenter study that will evaluate the changes in lung function (forced spirometry, measurement of static lung volumes using plethysmography and carbon monoxide pulmonary diffusion test) that patients admitted with pneumonia will present. by CoVid19 according to the level of severity at 4 and 26 weeks after hospital discharge. Restrictive pulmonary alterations will be confirmed by imaging tests (high resolution chest CT). The presence of immune response phenomena that lead to pulmonary fibrosis will be related to demographic and clinical variables and a series of biological markers, some of them already described as co-participants in the pathogenesis of pulmonary interstitial diseases, specifically of the idiopathic pulmonary fibrosis.