Community testing of SARS-CoV-2 protein markers

Purpose and goal The purpose of this project is to screen for circulating proteins related to SARS-CoV-2 infection. The aim is to validate protein marker panels on home-sampled microsamples and to identify protein markers that show past infection of SARS-CoV-2, using a single drop of blood. Expected results and effects We expect to be able to demonstrate the use of home sampling to screen for hundreds of protein markers from a drop of blood. Demonstrating the possibility of biomarker monitoring of home-sampled dried blood spot samples with the Olink panel opens up many new possibilities for screening populations for various diseases. Here we will demonstrate this with respect to SARS-CoV-2 but the future possibilities are potentially enormous as this allows screening of hundreds of proteins from a single drop of blood. Planned approach and implementation We will collect 1000 samples from patients in primary care as well as other volunteers and 1) screen for circulating protein markers related to infection of the new coronavirus. 2) Validate the use of Olink´s protein panels on home-sampled dried blood stains.