Quantifying Reactive Oxygen Species ( Like Nitric Oxide and Hydrogen Peroxide) in Exhaled Breath as Bio Fingerprints for Detection of Coronavirus

The present proposed project focuses on developing a chemiresistive biosensor as a biomarker to detect hydrogen peroxide and nitric oxide from human exhaled breath. In general, anything that is broken down by metabolism of the human cell is expressed in the breath with several ppm's. Thus, exhaled breath fingerprinting helps in identifying the infection in the patient even before the exposure of symptoms. In the present study, quantification of NO and H2O2 in the exhaled breath will be used as a biomarker to detect the possible coronavirus infection of the person. Further, the new breath testing device will enable the large scale testing of the persons by reducing the testing time significantly (within a minute). The current technology will also help in the diagnosis of the early stages, thus curtailing the spread of the virus, contributing to early treatment, and enabling high chances of recovery.