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Repositioning of drugs and in silico screening of certain compounds from natural resources to fight COVID-19 via molecular modeling methods

  • Funded by Agence Universitaire de la Francophonie (AUF)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2020

  • Funder

    Agence Universitaire de la Francophonie (AUF)

  • Principal Investigator

    N/A

  • Research Location

    Morocco

  • Lead Research Institution

    Université Hassan II de Casablanca

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Prophylactic use of treatments

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Project summary The project consists of carrying out two studies. The first concerns the in silico and in vitro study of the therapeutic effect of compounds extracted from natural sources widely used in Moroccan, Algerian and Cameroonian cuisine as additives, as well as as a remedy for certain diseases (Allium sativum, Zingiber officinale, Salvia rosmarinus, Aloe Vera, Artemisia Annua...). The second is devoted to repositioning existing drugs using molecular modeling methods. Goals Design of new molecules of natural origin likely to have a therapeutic effect against SARS-CoV-2. Proposal of drug candidates for SARS-CoV-2 based on existing drugs. Publication of 5 articles in peer-reviewed journals of Q1 or Q2 quality. Edition of a summary of the work carried out during this project. Development of patents.