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Evaluation of Polymorphisms of the ECA and ECA2 Genes in the Susceptibility to Serious Manifestations of Covid-19

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    FAPEG Brazil

  • Principal Investigator

    Gustavo Rodrigues Pedrino

  • Research Location

    Brazil

  • Lead Research Institution

    UFG

  • Research Priority Alignment

    N/A

  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease susceptibility

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Proposal presented by Gustavo Rodrigues Pedrino (UFG) aims to evaluate the influence of polymorphisms of the ECA and ECA2 genes on the susceptibility to the development of more aggressive manifestations and lethality by Covid-19 in a sample of hospitalized patients from the Goiás population, with a confirmed diagnosis of SARS-CoV-2 infection. The study proposes to evaluate the applicability of these polymorphisms as a tool to assist in decision making regarding the use of personalized medicine in combating and treating Covid-19.