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Evaluation of the infection of cells of individuals of different age groups with or without comorbidities by SARS-CoV-2 and the consequent production of antibodies

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    FAPEG Brazil

  • Principal Investigator

    Irmtraut Araci Hoffmann Pfrimer

  • Research Location

    Brazil

  • Lead Research Institution

    PUC-GO

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Unspecified

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The study presented by Irmtraut Araci Hoffmann Pfrimer (PUC-GO) aims to identify differences in the immune response in individuals with better or worse response to infection (age and presence of comorbidity). The research also intends to verify possible changes in the expression of the ACE2 protein may be related to epigenetic changes, for example. Thus, the work may provide subsidies for the search for drugs that could modulate the expression ACE2 or even modulate the production of neutralizing antibodies to SARS-CoV2.