Development of forecasting models, resources and safeguards to improve crisis preparedness: COVID-19 / Consortium: PREDICT

Grant number: 340541; 340551; 340539

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2023
  • Known Financial Commitments (USD)

    $1,278,194.93
  • Funder

    Academy of Finland
  • Principal Investigator

    Andrea Ganna,Laine, Liisa Ollila, Hanna
  • Research Location

    Finland
  • Lead Research Institution

    university of Helsinki; university of Helsinki; university of Helsinki
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Impact/ effectiveness of control measures

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The rapid and widespread spread of COVID-19 has had a particular impact on the economic and health crisis and security of supply, causing economic losses, morbidity and mortality. In our interdisciplinary research, we focus on raising crisis preparedness through economic, pharmaceutical and health care pathways. We will create a new harmonized register for assessing and predicting the effects of crises. We are developing forecasting models and tools to identify at an early stage the sectors and risk groups most affected by the direct and indirect effects of crises. Finally, we develop new ones and evaluate the effectiveness of existing safeguards. Our research creates new tools for managing the current crisis as well as preventive tools and forecasting models for future crises. The work is carried out at the University of Helsinki at the Finnish Institute of Molecular Medicine (Medicine and Health Sciences) and at the Faculty of Social Sciences (Economics).

Publicationslinked via Europe PMC

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity.

Face masks to prevent transmission of respiratory infections: Systematic review and meta-analysis of randomized controlled trials on face mask use.

Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription.

TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage.

Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress.

Electroporation of Labeled Antibodies to Visualize Endogenous Proteins and Posttranslational Modifications in Living Metazoan Cell Types.

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation.

Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression.

Co-translational assembly of mammalian nuclear multisubunit complexes.