Wastewater monitoring as a pandemic preparedness tool / Consortium: WastPan

Grant number: 339417; 339416; 339415

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2023
  • Known Financial Commitments (USD)

    $2,137,495.56
  • Funder

    Academy of Finland
  • Principal Investigator

    Annamari Heikinheimo, Sami Oikarinen, Tarja Pitkänen
  • Research Location

    Finland
  • Lead Research Institution

    university of Helsinki; University of Tampere; Department of Health and Welfare
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease transmission dynamics

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Infectious disease epidemics cause morbidity, death and economic loss in human communities. Epidemics can occur quickly or slowly. Pathogenic microbes, such as the new coronavirus that caused the COVID-19 pandemic, can spread rapidly. Multidrug-resistant bacteria, on the other hand, cause a so-called silent pandemic with a serious consequence: the depletion of effective drugs. WastPan develops science-based guidelines and preparedness tools for environmental monitoring of pathogen microbes and antibiotic resistance utilizing the wastewater network. We study a wide range of wastewater samples, the microbes they contain, and the metagenomics to determine the pathogens circulating and excreted into the wastewater. As a result, we will produce science-based recommendations and guidelines for wastewater-based surveillance aimed at detecting alert signs of communicable diseases in advance at different locations and at the national level to control epidemics.

Publicationslinked via Europe PMC

Clinically relevant sequence types of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae detected in Finnish wastewater in 2021-2022.

Clonal dissemination of successful emerging clone mecA-MRSA t304/ST6 among humans and hedgehogs in the Helsinki metropolitan area in Finland.

Phenotypic and genotypic characteristics of beta-lactamase dominant with CARBA, AmpC, and ESBL-producing bacteria in municipal wastewater influent in Helsinki, Finland.

Application of digital PCR for public health-related water quality monitoring.

Wastewater-based surveillance is an efficient monitoring tool for tracking influenza A in the community.

Detection and quantification of SARS-CoV-2 RNA in wastewater influent in relation to reported COVID-19 incidence in Finland.