Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) Clinical Research Network

  • Funded by Patient-Centered Outcomes Research Institute
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • Known Financial Commitments (USD)

    $28,000
  • Funder

    Patient-Centered Outcomes Research Institute
  • Principal Investigator

    Abel Kho
  • Research Location

    United States of America
  • Lead Research Institution

    Northwestern University?Center for Health Information Partnerships
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Recent data suggests the development of coagulopathy as a result of the inflammatory response to SARS-CoV-2 infection is associated with poorer outcomes in patients with COVID-19. The enhancement to this project utilizes the PCORnet Distributed Research Network Operations Center, vanguard Clinical Research Network (CRN) sites, and the PCORnet COVID-19 Common Data Model (CDM) to optimize and validate key COVID-19 data elements related to the treatment and outcomes associated with COVID-19 coagulopathy. This initial work will help to inform future work to better understand the prevalence and role of coagulopathy in COVID-19 and potential treatment options. In the enhancement: Vanguard CRN slides will load priority data elements into their PCORnet COVID-19 CDM PCORnet COVID-19 CDMs at participating sites will be assessed for research readiness Priority data elements will be validated by the CRNs through provenance surveys Coordinating Center and CRNs will perform limited validations of case definitions and derived data elements