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Proven Cancer Drugs Block Virus Reproduction

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Principal Investigator

    Prof Dr and Dr Jindrich Jinatl, Christian Münch

  • Research Location

    Germany

  • Lead Research Institution

    Goethe University and Frankfurt University Hospital

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Many viruses use and manipulate the communication channels of their host cells in order to promote their own reproduction. Biochemists and virologists from Goethe University and Frankfurt University Hospital have for the first time created an overall picture of the communication of a cell that is infected by SARS-CoV-2 viruses. In cell culture experiments, it was possible to stop the virus from replicating with a number of clinically proven cancer drugs. The drugs are applied at points where several communication channels of the cell meet. The Frankfurt team of scientists Prof. Dr. Jindrich Cinatl and Dr. Christian Münch patented via INNOVECTIS. INNOVECTIS is a subsidiary of the Goethe University Frankfurt and acts as a service provider for the transfer of academic know-how into business practice. "The successful use of active ingredients against SARS-CoV-2, which are components of already approved drugs, is a great opportunity to fight the virus."