Prevent Cell Entry
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Key facts
Disease
COVID-19Principal Investigator
Prof. Josef PfeilschifterResearch Location
GermanyLead Research Institution
Institute for General Pharmacology and Toxicology, University Hospital FrankfurtResearch Priority Alignment
N/A
Research Category
Therapeutics research, development and implementation
Research Subcategory
Pre-clinical studies
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
The penetration of SARS-CoV-2 viruses into body cells can possibly be influenced by drugs. Medicines that affect the metabolism of certain components of the cell membrane and thus prevent the entry of the virus and the death of cells caused by the virus. This option is investigated by a research project at the Institute for General Pharmacology and Toxicology. Possible points of attack for the development of suitable drugs for the treatment of an infection with SARS-CoV-2 are to be used. The Goethe Corona Fund made personnel and material resources available and raised further donations for the benefit of the project. "At the Center for Drug Research, Development and Safety ZAFES and the House of Pharma at Goethe University we have good conditions and a long tradition in pharmacological research. As luck would have it, my Ebola research, incidentally together with the virology department of the Philipps University of Marburg, yielded findings that we can now also use with SARS-CoV-2. "