Prevent Cell Entry

Grant number: unknown

Grant search

Key facts

  • Disease

    COVID-19
  • Principal Investigator

    Prof. Josef Pfeilschifter
  • Research Location

    Germany
  • Lead Research Institution

    Institute for General Pharmacology and Toxicology, University Hospital Frankfurt
  • Research Priority Alignment

    N/A
  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The penetration of SARS-CoV-2 viruses into body cells can possibly be influenced by drugs. Medicines that affect the metabolism of certain components of the cell membrane and thus prevent the entry of the virus and the death of cells caused by the virus. This option is investigated by a research project at the Institute for General Pharmacology and Toxicology. Possible points of attack for the development of suitable drugs for the treatment of an infection with SARS-CoV-2 are to be used. The Goethe Corona Fund made personnel and material resources available and raised further donations for the benefit of the project. "At the Center for Drug Research, Development and Safety ZAFES and the House of Pharma at Goethe University we have good conditions and a long tradition in pharmacological research. As luck would have it, my Ebola research, incidentally together with the virology department of the Philipps University of Marburg, yielded findings that we can now also use with SARS-CoV-2. "