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Reat Covid-19 With The Gene Scissors

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    Goethe University

  • Principal Investigator

    Dr and Prof Dr Manuel Kaulich, Jindrich Cinatl

  • Research Location

    Germany

  • Lead Research Institution

    Goethe University, University Hospital Frankfurt

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

A team of biochemists and virologists at the university hospital is investigating how the SARS-CoV-2 virus infects cells. The scientists want to find out which proteins in the human cell the virus needs in order to multiply in the cells. The two previously known proteins ACE2 and TMPRSS2 are apparently insufficient for viruses to penetrate cells and replicate there. This goes hand in hand with the search for human genes that are responsible for resistance to viral infection. In this way, the researchers want to find starting points for drug treatment of COVID-19.