Return to homepagePandemic Pact

No title

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Principal Investigator

    Alex K Shalek, Jose Ordovas-Montanes

  • Research Location

    United States of America

  • Lead Research Institution

    Broad Institute of MIT and Harvard

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Children (1 year to 12 years)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Researchers will study how the airways of pediatric patients respond to SARS-CoV-2 and common respiratory viruses to better understand COVID-19 disease in children. This project involves integral collaboration with clinicians at Boston Children's Hospital, and will profile 20 SARS-CoV-2 patients, 20 influenza patients, and 20 asymptomatic pediatric patients using computational tools to identify cells infected by these viruses. Determining what causes protective and detrimental cellular responses in infected patients may have an immediate impact on pediatric and adult health.