Return to homepagePandemic Pact

No title

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    Chan Zuckerberg Initiative

  • Principal Investigator

    Roser Vento-Tormo, Esteban Ballestar

  • Research Location

    United States of America

  • Lead Research Institution

    Wellcome Sanger Institute and Josep Carreras Research Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

In order to better understand immune response and progression of SARS-CoV2 infection, researchers will study samples from up to 50 COVID-19 patients using single-cell transcriptomics methods. Patients will include those with autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, psoriasis, and multiple sclerosis, as well as immunodeficient patients diagnosed with common variable immunodeficiency. In addition, autoimmune/immunodeficiency patients without COVID-19 and COVID-19 patients without any pre-existing immunodeficiency will serve as controls.