Vaccine Effectiveness of Variants in British Columbia

The Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) has harmonized data collection for COVID-19 tested patients across 50 emergency departments in 8 provinces, including BC. This new project will leverage CCEDRRN's existing and growing registry infrastructure to determine the real-world effectiveness of vaccines in BC in reducing severe COVID-19, as documented by emergency admission. Research efforts will specifically focus on vaccine effectiveness against the P.1 Variant of Concern circulating in BC, and on effectiveness of a single dose to assess outcomes of Canada's dose delay. This study will provide critical real-world data about vaccine performance and support key study sites in the Lower Mainland