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Why do only some patients develop severe COVID-19 following infection with SARS-CoV-2?

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Principal Investigator

    Conjoint Professor Stuart Tangye

  • Research Location

    Australia

  • Lead Research Institution

    St Vincent's Clinical School & Garvan Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

By using cutting edge molecular, genomic, transcriptomic and cellular technologies, we will determine the genetic basis of severe COVID-19. This will identify non-redundant signaling pathways and immune cells critical for robust host responses against SARS-CoV2. Outcomes from this study will enable the development of novel prophylactic and therapeutic strategies for severe viral infections.