Creation of viral growth inhibitors targeting SARS-CoV-2 protease | Pandemic PACT Tracker

Key facts

Disease
COVID-19
Start & end year
2021
2024
Known Financial Commitments (USD)
$37,440
Funder
KAKENHI
Principal Investigator
Hoshino Tadashi Hoshino
Research Location
Japan
Lead Research Institution
Chiba University
Research Priority Alignment
N/A

Research Category
Therapeutics research, development and implementation
Research Subcategory
N/A
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

6 Publications linked via Europe PMC

Last Updated:4 days ago

View all publications at Europe PMC

Structural Analysis of HIV-1 RNase H Bound to a Galloyl Active Site Inhibitor and Computational Compound Modification.

Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis.

Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase.

Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.

Quantifying the Separation of Positive and Negative Areas in Electrostatic Potential for Predicting Feasibility of Ammonium Sulfate for Protein Crystallization.

Secondary Structure and Conformational Stability of the Antigen Residues Making Contact with Antibodies.