Clinical characteristics, management and outcomes of COVID-19 patients in Indonesia: Clinical features protocol (INACO Study)

The global pandemic COVID-19/SARS-CoV-2 affects low- and middle-income countries (LMICs) differently, but rigorously designed studies of clinical management and outcomes are still lacking. its to these countries. With the world's fourth-largest population (270 million), Indonesia is facing enormous challenges, especially in Jakarta, and other hotspots, with the highest mortality rates by region. This epidemic shows no signs of abating. A systematic approach is urgently needed to "do and learn" by describing clinical patterns, management and outcomes of hospitalized COVID-19 patients, analyzing in the context of to continuously improve the national response to the epidemic. We propose the establishment of a prospective observational cohort study of hospitalized COVID-19 patients in Jakarta, Indonesia to provide this critically needed evidence. This study also establishes a foundation for the study of the pathophysiology and therapeutic intervention research in the near future. - Purpose and goals To describe current clinical patterns, severity, and management of patients with COVID-19, predict disease outcome and identify factors associated with that outcome in Indonesia. To inform local practice and national policy on the basis of this evidence and identify specific gaps in care. To establish a COVID-19 clinical research platform for studies and trials.