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Use of melatonin against COVID-19 - induced pneumonia

  • Funded by Philippine Council for Health Research and Development (PCHRD)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    Philippine Council for Health Research and Development (PCHRD)

  • Principal Investigator

    Unspecified Unspecified Unspecified

  • Research Location

    Philippines

  • Lead Research Institution

    Manila Doctors Hospital (MDH)

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Supportive care, processes of care and management

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Unspecified

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

To support the current efforts against the pandemic, this project led by Dr. Rafael R. Castillo of Manila Doctors Hospital (MDH) seeks to probe whether administering high doses of melatonin (hdM), a hormone that regulates sleep-wake cycle, will lessen the need for intubation or ventilation support of hospitalized COVID-19 patients and ultimately improve the survival rate against the infection. In 2020, the pilot study done for the project has been accepted for publication in the Melatonin Research Journal, which observed that patients given with melatonin showed faster clinical improvement. The project ran for four months in selected hospitals in Metro Manila and Cebu City.