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Human iPSCs and Organ Chips Model SARS-CoV-2-Induced Viral Myocarditis

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    American Heart Association

  • Principal Investigator

    Unspecified Unspecified Unspecified

  • Research Location

    United States of America

  • Lead Research Institution

    Cedars-Sinai Medical Center

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This team will investigate whether SARS-CoV-2 can directly infect human cardiomyocytes, assess resulting effects and seek to establish a cardiomyocyte-specific antiviral drug screening platform against SARS-CoV-2. The findings potentially may lead to development of novel therapeutics for the cardiac-specific effects of COVID-19.