What's the Risk from and to European wildlife from SARS-like Coronaviruses?

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:9 publications

Grant number: BB/W009501/1

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2021
    2022
  • Known Financial Commitments (USD)

    $373,160.96
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    Rachael Tarlinton
  • Research Location

    United Kingdom
  • Lead Research Institution

    University of Nottingham
  • Research Priority Alignment

    N/A
  • Research Category

    Animal and environmental research and research on diseases vectors

  • Research Subcategory

    Animal source and routes of transmission

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The current COVID-19 human pandemic had its origins in SE Asian wildlife, and although the natural, endemic host remains unknown (most likely bats), onward transmission from humans to other species including large outbreaks in farmed mink and cases in domestic cats keep occuring . The outbreak in mink in Europe and the USA with transmission back to humans has raised the spectre of the virus establishing itself in other animal hosts, creating a new reservoir for the virus, with potentially serious consequences for both humans and affected animals. Europe is home to a large number of wild mustelid species, including feral mink, along with bats known to carry SARS-like viruses and cricetid rodents thought to be susceptible to SARs-CoV2. However, we currently have no idea whether any virus spill-over or circulation is occurring in these animals. This project will perform PCR based screening of faecal and lung samples from the highest risk wildlife species for SARS-CoV-2 like viruses in the UK (bats, mustelids and cricetid rodents), including retrieval of full virus sequences from any positive animals using NGS sequencing techniques (Illumina and Nanopore). The project will determine: a) If SARS-COV-2 spill-over from humans into wildlife is currently occurring b) What other coronaviruses these animals are carrying This will enable decisions to be made as to whether SARS-CoV-2 circulation in European wildlife represents a real risk to the human population and/or to wildlife, and if monitoring or mitigation programmes are necessary

Publicationslinked via Europe PMC

Genomic characterization and cross-species transmission potential of hedgehog coronavirus.

Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom

Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom.

Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus.

Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21

Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus

Sarbecoviruses of British horseshoe bats; sequence variation and epidemiology.

Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology

Mustelid samples needed for coronavirus testing.