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Large Scale Production of SARS CoV2/COVID-19 Proteins and Development of Antibodies for Serological Tests.

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    BIRAC

  • Principal Investigator

    Sujay Singh

  • Research Location

    India

  • Lead Research Institution

    IMGENEX India Pvt. Ltd.

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Not applicable

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Validated serologic assays are crucial for patient contact tracing, identifying the viral reservoir hosts, epidemiological studies, evaluation of results of vaccine trials and development of therapeutic antibodies. Hence, a steady supply chain of the high quality reagents are essential for developing diagnostic kits, research on therapeutics and vaccine development. Here, we propose to produce S and N two major antigens of SARS-CoV2 in amounts that will help to develop at least two million diagnostic kits per antigen per month for supplying to Indian manufactures of diagnostic kits apart from developing monoclonal antibodies against structural proteins of SARS-CoV2.