COVID-19 RAPID RESPONSE: ANTIVIRAL COATING FOR THE INACTIVATION OF SARS-COV-2 IN FOOD MANUFACTURING AND LIVESTOCK PRODUCTION

NON-TECHNICAL SUMMARY: In the United States, transmission of SARS-CoV-2 has been predominant in large manufacturing operations that are designated as providing "essential" services. These operations, particularly food production and meatpacking facilities, have been "hot spots" for infection. Since early 2020, COVID-19 cases among U.S. workers in 115 meat and poultry processing facilities have been reported by 19 states. Ensuring a safe environment for workers is essential for a sustained and safe food supply, particularly during pandemics like COVID-19. Through its proprietary nanoparticle coating process, Claros Technologies Inc is able to impart antiviral properties on a wide variety of surfaces and materials. This SBIR Phase 1 project aims to develop, demonstrate and implement antiviral coating for surfaces in food manufacturing plants and livestock production sites. Antiviral surfaces such as plastic films, metal work surfaces, and porous materials will be tested on animal coronavirus analogues as well as SARS-CoV-2. Efficacy will be determined my monitoring viral inactivation after immediate and long-term contact on the treated surfaces. Durability of the coatings will be assessed with prolonged use and after washing. Finally, best use criterion for the coatings and coated materials will be determined for rapid implementation in food production facilities. The ultimate goal of this project is to produce stable coatings that deactivate viruses including SARS-CoV-2 on contact and maintain performance over long periods. Furthermore, the project will inform best practices for installation, maintenance, and use of coated surfaces. Enabling a sterile, virus-free environment in food manufacturing and animal agriculture is a key tool in curbing the transmission of COVID-19, promoting worker health and safety, and maintaining a secure food system.