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Therapeutic approach against human and feline coronaviruses]

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    Other Funders (France)

  • Principal Investigator

    Sophie and Hakim Le Poder and Ahmed-Belkacem

  • Research Location

    France

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Coronaviruses are viruses that cause fatal diseases in humans and animals for which there is no specific treatment. The objective of this research project is to study the therapeutic potential of new antiviral molecules against Coronaviruses. The mechanisms of action of these molecules will be investigated. The study will be conducted on a human coronavirus responsible for respiratory infections and a feline coronavirus which causes a fatal disease in cats. In addition, the most effective molecules can be tested in vivo in naturally infected cats for which no therapy is currently possible. These data will allow the effective therapeutic dose against Coronaviruses to be evaluated in vivo in a relevant model.