FINDER VIRUS. Diagnosis by metabolomics, platelet aggregation

The quick and low-cost diagnosis of infections by SARS-CoV-2 and influenza virus can allow the adoption of measures to control transmission both in the environment of Health Units and isolation from social contact in the community. In addition to the specific diagnosis, the early identification of patients at higher risk of death also allows for a targeted therapeutic approach with ventilatory support measures and the use of specific antivirals against these two viruses. Antiviral drugs are known to have a clinical impact only when administered in the first days of symptoms of influenza virus infections, and possibly also of SARS-CoV-2. Otherwise, the rapid identification of patients at high risk of death allows patients to be referred from primary or secondary health care units to more complex ones. In this project, we will develop a diagnostic method for SARS-CoV-2 and Influenza virus infection through metabolomic analysis. We will also carry out a prognostic study of patients diagnosed with SARS-CoV-2 and Influenza virus infection with severe acute respiratory syndrome