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PHYSICAL TRAINING AND COVID-19

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    University of São Paulo

  • Principal Investigator

    N/A

  • Research Location

    Brazil

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    N/A

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Recent studies indicate that cities at higher altitudes, with low oxygen levels, have a lower number and reduced severity in cases of COVID-19. Activation of hypoxia-inducible factor 1α (HIF-1α) can decrease the expression of ACE 2, identified as a facilitator of the entry of the SARS-CoV 2 virus into cells; and, increase the production of erythropoietin, with benefits that can counteract the negative effects of COVID-19. Physical training can improve the immune system and cardiorespiratory capacity. In this sense, physical training with hypoxic stimulation appears as an alternative that supports conventional treatments for recovery of these patients. The aim of this study is to analyze the effects of moderate intensity training in intermittent normobaric hypoxia on health parameters in people convalescing from COVID-19.