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Evaluation of the effects of the renin angiotensin system in COVID-19-induced acute respiratory distress syndrome.

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    University of São Paulo

  • Principal Investigator

    Unspecified Unspecified Unspecified

  • Research Location

    Brazil

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Supportive care, processes of care and management

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Objective to evaluate the effect of using ACE inhibitors in patients with a positive diagnosis for SARS-COV-2, correlating with their clinical evolution; and to analyze the acute effect of ACE and ACE2 inhibitors in mice submitted to pneumonia through the systemic administration of lipopolysaccharide (LPS) model after administration of ACE2 blockers.