ACE2 diversity in placental mammals reveals the evolutionary strategy of SARS-Cov-2

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $0
  • Funder

    University of São Paulo
  • Principal Investigator

    N/A

  • Research Location

    Brazil
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Animal and environmental research and research on diseases vectors

  • Research Subcategory

    Animal source and routes of transmission

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

SARS-CoV-2 is highly "generalistic" regarding its ability to infect humans, any individual from any population, at least considering its gateway to the cell, the ACE2 protein. On the other hand, it is not a "generalist" type coronavirus capable of naturally and easily infecting a variety of other species, including pets.