Enhanced laboratory support to perform assessment of vaccine effectiveness against SARS-Co-V-2 infection
- Funded by Estonian Research Council
- Total publications:0 publications
Grant number: VMVPT21550
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Key facts
Disease
COVID-19Start & end year
20212022Known Financial Commitments (USD)
$144,147.37Funder
Estonian Research CouncilPrincipal Investigator
Unspecified Unspecified UnspecifiedResearch Location
EstoniaLead Research Institution
University of TartuResearch Priority Alignment
N/A
Research Category
Vaccines research, development and implementation
Research Subcategory
Characterisation of vaccine-induced immunity
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Adults (18 and older)
Vulnerable Population
Unspecified
Occupations of Interest
Health Personnel
Abstract
In order to assess the shortcomings and strengths of the vaccination plan, it is critical to evaluate the efficacy of the vaccines in normal use (public health practice). The effectiveness of a vaccine in real-world vaccine effectiveness (VE) is affected by a number of factors, including the transport, storage and administration of the vaccine to patients. Young people and healthy people are usually recruited for clinical trials of vaccines, while in real life the vaccine is used primarily by older people and people with chronic diseases. The efficacy of the vaccine in different age and risk groups, the duration of the protective effect, the effectiveness in preventing transmission, the relative effectiveness compared to other vaccines can be evaluated in routine VE studies. relationship to the number and timing of doses administered and efficacy against new strains of SARS-CoV-2. The main aim of the study was to evaluate the effectiveness (CO) of the COVID-19 vaccine in hospital staff. Secondary Objectives: To measure the efficacy (VE) of a product-specific COVID-19 vaccine among hospital staff based on: (i) the number of doses administered; (ii) the time of the last dose; (iii) the age of the employee; (iv) the employee's position and / or department; (v) whether or not the employee has direct contact with patients.