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the sySTEMs initiative : systems biology-augmented, stem cell-derived, multi-tissue panel for rapid screening of approved drugs as potential COVID-19 treatments

  • Funded by Australian Government (Australian Research Council)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2021
    2024

  • Known Financial Commitments (USD)

    $736,387.33

  • Funder

    Australian Government (Australian Research Council)

  • Research Location

    Australia

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Prophylactic use of treatments

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Vaccines alone can't stop COVID-19 infections; we also need safe, effective and affordable COVID-19 treatments urgently. A great strategy is to repurpose drugs already approved for other diseases. To do that we need rapid, high-throughput drug screening in relevant tissues grown from 'stem cells'. However, this system needs improvement in its readouts, reproducibility and clinical correlation. We intend to achieve this and screen the 3 most promising repurposed drug candidates within a year.